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Essential fatty acids for ADHD - Literature Review & Commentary - Brief Article

Alan R. Gaby

Forty-one children (aged 8-12 years) with attention deficit-hyperactivity disorder (ADHD) and specific learning difficulties (mainly dyslexia) were randomly assigned to receive, in double-blind fashion, an unsaturated fatty acid supplement or placebo (olive oil) for 12 weeks.

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Fish Oil
Fish oil contains omega-3 fatty acids, one of the two main classes of essential fatty acids. (Omega-6 fatty acids are the other main type.) Essential fatty acids are special fats that the body needs as much as it needs vitamins .

News 14 Carolina | 24 Hour Local News | HEALTH
No parent wants her child taking a daily dose of drugs. But drugs are all many parents of kids with ADD or ADHD are left with. That has many looking to alternative ways to help their children.

News 14 Carolina | 24 Hour Local News | HEADLINES
No parent wants her child taking a daily dose of drugs. But drugs are all many parents of kids with ADD or ADHD are left with. That has many looking to alternative ways to help their children.

News 14 Carolina | 24 Hour Local News | TOP STORIES
No parent wants her child taking a daily dose of drugs. But drugs are all many parents of kids with ADD or ADHD are left with. That has many looking to alternative ways to help their children.


The supplement provided daily: 186 mg of eicosapentaenoic acid (EPA), 480 mg of docosahexaenoic acid (DHA), 96mg of gamma-linolenic acid (GLA), 60 IU of vitamin E, and 864 mg of linoleic acid. Compared with placebo, active treatment significantly improved symptom scores related to both cognitive problems and behavioral abnormalities. No adverse effects were seen.

Comment: Previous studies have shown that boys with ADHD have lower concentrations of certain fatty acids in plasma lipids and red blood cells than do healthy children. As both omega-3 and omega-6 fatty acids play a role in normal brain function, it is possible that essential fatty acid deficiency is involved in the pathogenesis of ADHD. The results of the present study indicate that supplementation with a combination of omega-3 and omega-6 fatty acids may be beneficial in the treatment of ADHD and associated learning disabilities. It is not clear which fatty acids in the supplement were responsible the improvement. In previous studies, evening primrose oil alone (a source of GLA and linoleic acid) and DHA alone provided little or no benefit for children with ADHD. Those findings suggest that the main active ingredient in the present study was EPA, or that a combination of omega-3 and omega-6 unsaturated fatty acids is more effective than the supplements used in earlier studies. Richardson AJ, et al. A rando mized double-blind, placebo-controlled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specific learning difficulties.

Prog Neuropsychopharmacol Biol Psychiatry 2002;26;233-239.

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